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DeCS
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Descriptor English:
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Genes, myb
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Descriptor Spanish:
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Genes myb
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Descriptor Portuguese:
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Genes myb
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Synonyms English:
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c-myb Genes
myb Genes
v-myb Genes
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Tree Number:
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G14.340.024.340.383.500.791.418
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Definition English:
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Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995). |
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History Note English:
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2000; use ONCOGENES 1985-1999
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Allowable Qualifiers English:
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Record Number:
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34576
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Unique Identifier:
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D020570
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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